Millions of people worldwide suffer from heartburn and gastrointestinal discomfort, which can result from stress, eating too much, and/or eating too fast. Symptoms can include burning and pressure, or pain in the chest and or throat area. Many people treat this condition through the use of antacids. Antacids function by neutralizing stomach acid, which raises the pH of the stomach. Antacid products are very popular because they generally are able to provide relief quite quickly. Calcium carbonate, which is the antacid chosen for this formula, is a naturally occurring mineral that is commonly used to neutralize stomach acid.
Though stomach acid can cause significant discomfort, it is also very important for digestion. The acidity of the stomach must reach a sufficiently low pH in order for pepsinogen to be converted to its active form, which is the proteolytic enzyme pepsin. Disrupting the low pH environment of the stomach may actually exacerbate pancreatic insufficiency, which is one of the potential underlying conditions that can contribute to indigestion. In order to compensate for this potential problem, a proprietary blend of digestive enzymes was added to support normal digestion, which enhances the functionality of this product.
Happy Gut Be Cool includes a special blend of digestive enzymes that is designed specifically to support digestion. It is a proprietary blend of proteolytic, lipolytic, and carbohydrolytic enzymes to aid in the digestion of nutrient dense meals. Enzyme supplementation can be critical in handling the increased digestive demands placed on the body by our modern diets. Supplemental enzymes also help ensure that the maximum amount of available nutrition is obtained from the food eaten. Supplemental enzymes are used to replace the enzymes that are either lost in cooking or during processing. The heat of these processes destroys the enzymes that were already present in the food. Without these enzymes, the full digestive load of the meal falls on the digestive system, which can result in considerable gastrointestinal stress. In addition to the problems that food processing causes, the heavy use of antacids can have a deleterious effect on pepsin production, leading to a need for supplemental enzymes. The enzymes in can function over a relatively broad pH range, making them a perfect complement to calcium carbonate, which was added to this formula for its acid-neutralizing properties. Antacids such as calcium carbonate are widely used for their ability to relieve the discomfort associated with heartburn.
Protease (from Aspergillus oryzae) is a mixture of acid, neutral and alkaline proteases that demonstrates both exo-peptidase and endo-peptidase activity with high substrate specificity. This mixture contains a protease that has a high exo-peptidase level which allows the user to obtain a high degree of protein hydrolysis without formation of bitter products. These proteases have an effective pH range from 2.75 to 7.5. For this reason, this mixture of proteases works synergistically with endogenous enzymes to provide protein digestion throughout the entire digestive tract.
Protease (from Aspergillus niger) is characterized by its ability to hydrolyze proteins under acid conditions. The broad specificity of acid-stable protease enables the enzyme to, easily and efficiently, hydrolyze most soluble proteins. Because protease 3.0 has an effective pH range of 2.75 to 4.7, it is uniquely suited to work synergistically with endogenous pepsin to provide protein digestion in the stomach.
Neutral Bacterial Protease (from Bacillus subtilis) is an endopetidase that hydrolyzes the interior bonds of most soluble proteins. Neutral bacterial protease has an effective pH range from 5.5 to 8.5, and works synergistically with endogenous enzymes to provide protein digestion primarily in pyloric region of the small intestine.
The proteolytic enzymes used in this formula helps to digest protein to produce amino acids, which are important building blocks in the human body. The amino acids are used to build muscles, metabolic enzymes, neurotransmitters, and many other essential biochemicals. Proteolytic supplementation can be essential in digesting the extra protein consumed during the course of a typical modern diet. Proteolytic enzyme supplementation may also be an important factor in maintaining lean muscle tissue.
Amylase will randomly hydrolyze the interior alpha- 1,4-glucosidic bonds of starch to release simple sugars for digestion. This enzyme works synergistically with endogenous human amylase to digest starchy foods.
Glucoamylase will hydrolyze terminal 1,4-linked alpha-D-glucose residues successively from non- reducing ends of amylose chains to release free glucose. This enzyme also possesses the ability to hydrolyze alpha-1,6-glucosidic linkages in isomaltose and dextrins. This enzyme works synergistically with endogenous human amylase and supplemental amylase to potentiate the complete digestion of carbohydrate rich foods.
Invertase is characterized by its ability to catalyze the inversion of sucrose solution. This enzyme catalyzes the hydrolysis of sucrose into its component parts D- fructose and D-glucose. This action helps in the digestion of refined sugars that are common in modern diets.
Diastase is characterized by its ability to hydrolyze amylose and other polysaccharides to remove successive maltose units (glucose-glucose dimers) from the non-reducing end. This enzyme works synergistically with amylase and glucoamylase to digest carbohydrate rich foods, particularly those produced from grains.
This combination of carbohydrases is designed to assist with carbohydrate digestion. This combination allows a more complete digestion of the carbohydrates consumed, which enables a person to properly digest and receive the maximum amount of nutrients available from their carbohydrate intake.
Lipase catalyzes the hydrolysis of triglycerides of simple fatty acid esters, yielding mono- and diglycerides, glycerol and free fatty acids. This blend of lipases is able to catalyze the hydrolysis of fatty acids from all three positions of the triglyceride, making for a more complete digestion of the triglyceride. It has broad substrate specificity on the fats and oils of vegetable and animal origins. These lipases work synergistically with endogenous enzymes to help digest fatty foods.
Supplementing with Lipase can help the body to properly digest the excessive fat being eaten in today’s typical high fat, high carbohydrate diet. Considerable digestive distress and even malabsorption of nutrients such as vitamins A and E can result from improper fat digestion.
Calcium Carbonate is used for the neutralization of stomach acid (HCl). This reaction forms calcium chloride, carbon dioxide, and water. In addition to being used for stomach acid neutralization, calcium is the most abundant mineral in the human body. Calcium plays vital roles in numerous body functions, including enzyme activation, muscle contractions and nerve impulse transmissions. The bones act as the primary reservoir for this essential mineral, storing up to 99% of the body’s calcium. Because bodily processes cause blood levels of this essential mineral to fluctuate regularly, calcium is constantly moving in and out of the bones to maintain normal levels of serum calcium. To keep this process from resulting in a net loss of calcium from the bones, the diet must provide enough calcium to replace that which is lost from the bones when blood calcium levels dip. A diet that is chronically deficient in calcium will ultimately deplete the bone’s mineral stores, leading to osteoporosis. Scientific research suggests that calcium is necessary for strong bones and teeth, proper muscle contractions, and nerve impulse transmissions.